It is the turn of the century. The widowed Lady Anna Winterbourne meets Sharif Pash al-Barudi, an Egyptian nationalist in Cairo. She represents the antithesis of everything he stands for but they fall in love and marry. Intertwined with their story is the story of Isabel Parkman, an American divorcee and Omar-al-Ghamrawi, both descendents of Anna and Sharif, who face the same challenges to their love. Through Anna’s letters and journals, Omar’s sister Amal and Isabel piece together the tales of love across cultures and different generations.